SOP For Cleaning and Sanitization of RO Water System (Plant)

1.0 OBJECTIVE

1.1 To lay down the procedure for Cleaning and Sanitization of RO water & Process water. 

2.0 SCOPE

2.1 This procedure applies to the Production of ‘’XYZ company.

3.0 RESPONSIBILITIES

3.1 Maintenance Officer / Shift Officer & online QA to follow the SOP.

3.2 Head – Production & QA for complies of SOP.

4.0 PROCEDURE

4.1  CLEANING OF RO WATER & PROCESS WATER         

4.1.1 Switch off the main power supply of RO water tank and process water tank. 

4.1.2 Hang the tag of ''MAN AT WORK DO NOT OPERATE'' on an electrical panel. 

4.1.3 Empty the tank completely through the bottom drain line. 

4.1.4 Clean the inside of the tank, from top to bottom, using hot water. 

4.1.5 Drain the washings through a bottom drain line.

4.2 SANITIZATION OF RO WATER & PROCESS WATER 

4.2.1 For disinfection, use Sodium Hypo chloride solution of strength 200 ppm available chlorine.

4.2.2 Contact time with hypo chloride solution should be 5 minutes minimum, but in no case, should it exceed 10 minutes.                                         

4.2.3 Drain disinfectant solution from the bottom of the tank within 6-10 min. Ensure that the tank is completely drained.

4.2.4 As soon as draining is over, give a final rinse with 80⁰ C water (The tank is now ready for use)     

4.3 PREPARATION OF 200 PPM SODIUM HYPOCHLORITE SOLUTION

4.3.1 Add 5ml of 4% sodium hypo chloride in 1000 ml water

4.3.2 Fill the record in Equipment sanitization record format.

4.4 FREQUENCY: Half Yearly 

Note: Do not use Formalin for sanitization.

5.0 ABBREVIATIONS

 SOP:  Standard Operating Procedure

 QA: Quality Assurance

 No.: Number

IPA: Iso Propyl Alcohol 

4.2 SANITIZATION OF CONTAINERS, SPATULAS, TROLLEYS & BARREL PUMPS    

4.2.1 Preparation of solution:

4.2.1 (10.1%) Carbendazim Slution-100mg of carbendazim powder in 100ml of IPA solution.

4.2.2 Spray 0.1% carbendazim solution.

4.2.3  After half an hour of spray, the equipment can be used.

4.2.4 Fill in the record of cleaning & sanitization.

4.2. The overall process should be checked by an authorized person.